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Preparation of dummy molecularly imprinted polymers for selective extraction of aromatic amine genotoxic impurities

Xiaoya Fu,Xia Wang,Zhining Xia,Yike Huang

Journal of Chromatography A（2022）

Cited 2|Views4
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Abstract
•Using dummy template MIT to pretreat sample contained GTIs.•A strategy of selecting the dummy template molecule by computer simulation.•Dummy template MIP shows a good selection on a group of GTIs.•Dummy template MIP gives a potential application in detection of GTIs in drugs.
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Key words
Molecular imprinting,Dummy template,Genotoxic impurities,2,6-dichloroaniline,p-Toluidine
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