Preparation of dummy molecularly imprinted polymers for selective extraction of aromatic amine genotoxic impurities
Journal of Chromatography A(2022)
Abstract
•Using dummy template MIT to pretreat sample contained GTIs.•A strategy of selecting the dummy template molecule by computer simulation.•Dummy template MIP shows a good selection on a group of GTIs.•Dummy template MIP gives a potential application in detection of GTIs in drugs.
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Key words
Molecular imprinting,Dummy template,Genotoxic impurities,2,6-dichloroaniline,p-Toluidine
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