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Renin-angiotensin system blockers affect cognitive decline in Parkinson's disease: The PPMI dataset

Jianhua Yang,Yuyuan Gao,Qingrui Duan,Yihui Qiu,Shujun Feng,Cuijing Zhan,Yin Huang,Yuhu Zhang,Guixian Ma,Kun Nie,Lijuan Wang

Parkinsonism & Related Disorders（2022）

Cited 4|Views9
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Abstract
•Angiotensin receptor blockers improved global cognitive function in PD patients with hypertension.•No significant impact of rennin angiotensin system blockers on biomarkers in CSF were observed.•Rennin angiotensin system blockers reduced [18F] florbetaben uptake in cortex and subcortex nuclei in the brain.
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Parkinson's disease,Renin-angiotensin system,Angiotensin receptor antagonists(ARBs),Angiotensin converting enzyme inhibitors(ACEIs),Cognition,CSF biomarker,18F florbetaben PET scan
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