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Plasmid evolution in the clinic

Rosanna C. T. Wright,Michael A. Brockhurst

Nature Ecology & Evolution（2022）

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Abstract
Plasmids are well known for transferring antibiotic resistance genes between bacteria. A study in the clinic shows that evolutionary dynamics within the gut microbiomes of hospitalized patients lead to rapid adaptive changes, balancing the level of resistance that plasmids provide against the fitness costs that they impose on bacteria.
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Key words
Antimicrobials,Molecular evolution,Life Sciences,general,Ecology,Evolutionary Biology,Zoology,Paleontology,Biological and Physical Anthropology
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