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Hydrocortisone may act through the angiotensin II receptor-2 level in patients with catecholamine-resistant septic shock.

Seyma Baykan,Murat Bicakcioglu,Nilüfer Bulut,Neslihan Yucel,Yasemin Ersoy,Nermin Kibrislioglu Uysal,Ayse B Ozer

Minerva anestesiologica（2023）

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Abstract
It was concluded that angiotensin II and AT1 can be used as a biomarker of refractory septic shock and hydrocortisone may provide their blood pressure correcting effect by reducing AT2 level in these patients. AT2 can be a therapeutic target in the catecholamine-resistant septic shock patients.
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Key words
Angiotensin II, Hydrocortisone, Shock, septic
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