Discontinuing Directly Acting Antivirals During Hepatitis C Treatment: Highlighting an Infrequent but Hostile Event.

Mohamed El-Kassas,Sherif Elbehiry, Enas Rezk,Dalia Omran,Ahmed Sherief,Mohamed Eltabbakh,Inas Moaz,Adel El Tahan,Mohammad Abdalgaber, Haidy Khalil,Mohamed Alboraie,Amr El Fouly,Mohammed Aboul-Ezz,Amany Wahb, Ahmed Madkour

Clinics and research in hepatology and gastroenterology（2022）

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摘要

• Treatment of chronic hepatitis C virus (HCV) with new direct-acting antiviral agents (DAAs) has been proven efficacious and safe in many clinical trials . • Several factors influence patient compliance with DAAs, and cause treatment discontinuation, resulting in waste of money and effort that could exhaust the health care system. • Treatment regimen, longer treatment duration, and unfavorable liver functions were associated with treatment discontinuation.

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antivirals,treatment

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