Alloplastic Reconstruction of the Mandible after Subtotal Mandibulectomy for Medication-Related Osteonecrosis of the Jaw. An Update of the Method

SSRN Electronic Journal(2022)

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摘要
Background: Reconstruction of continuity defects following osteonecrosis in multimorbid patients is challenging. In all cases of the predescribed palliative treatment method for alloplastic mandible reconstruction, plate fractures were detected in follow-up. We hypothesized that a modification could avoid these fractures, leading to stable long-term results.Methods: This retrospective study compares the original method with a modification using single, laser-sintered CAD-CAM plates instead of manually bent miniplates. The predescribed shuttering technique was used to reconstruct the mandible in its original shape with bone cement.Results: Uneventful wound healing was observed in 86% of the cases after modification of the method. No implant or plate fracture occurred.Conclusions: The presented method should be considered as a treatment option for mandible reconstruction in elderly, multimorbid patients in palliative situations. The results of this study suggest that the modification of the method leads to significantly improved long-term stability. Donor site morbidity is avoided with this method of palliative surgery.
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关键词
alloplastic reconstruction, ARONJ, mandible reconstruction, medication-related osteonecrosis of the jaw, MRONJ, Palacos & REG, reconstruction
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