Design, synthesis and biological evaluation of novel substituted indazole-1,2,3-triazolyl-1,3,4-oxadiazoles: Antimicrobial activity evaluation and docking study

Ananda Kumar Dunga,Tejeswara Rao Allaka,Yugandhar Kethavarapu,Sunil Kumar Nechipadappu, Pradeep Pothana,Kishore Ravada,Jajula Kashanna,Pilli V.V.N. Kishore

Results in Chemistry（2022）

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Abstract

•A library of indazole derivatives have synthesized and characterized by spectroscopic techniques.•All the novel synthesized compounds were screened for their antimicrobial activities.•All designed scaffolds are displayed promising antimicrobial activity.•Molecular modeling of prepared ligands into active site of S. aureus with 2ZCS.

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Key words

Indazole,1,2,3-Triazoles,1,3,4-Oxadiazoles,Antibacterial activity,Antifungal activity,2ZCS

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