Effector Memory-Expressing CD45RA (TEMRA) CD8 + T Cells from Kidney Transplant Recipients Exhibit Enhanced Purinergic P2X4 Receptor-Dependent Proinflammatory and Migratory Responses.
Journal of the American Society of Nephrology : JASN（2022）
摘要
Our findings highlight the active role of TEMRA CD8 T cells in humoral transplant rejection and suggest that kidney transplant recipients may benefit from therapeutics targeting these cells.
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关键词
adhesion molecule,cell activation,cell adhesion,chemokine,chronic allograft rejection,endothelium,immunology,kidney transplantation,lymphocytes,purinergic P2X4 receptors
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