Zebrafish Galectin 3 binding protein (Lgals3bp) is the target antigen of the microglial 4C4 monoclonal antibody

Mireia Rovira,Magali Miserocchi,Alice Montanari, Latifa Hammou,Laura Chomette,Jennifer Pozo,Virginie Imbault,Xavier Bisteau,Valérie Wittamer

Developmental Dynamics（2022）

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摘要

The 4C4 monoclonal antibody recognizes Lgals3bpb, a predicted highly glycosylated protein whose function in the microglial lineage is currently unknown. Identification of Lgals3bpb as a new pan-microglia marker will be fundamental in forthcoming studies using the zebrafish model.

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关键词

MAC-2BP,brain,lectin,macrophages,proteomics,zgc:112492

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