2 PRONUCLEI (2PN) BANKING AS A METHOD TO OPTIMIZE COSTS FOR POOR PROGNOSIS PATIENTS DOING MULTIPLE CYCLES WITH PRE-IMPLANTATION GENETIC TESTING FOR ANEUPLOIDY (PGT-A) LEADS TO SIMILAR BLASTOCYST YIELD

With lower ovarian reserve and increased rates of aneuploidy, older patients undergoing in-vitro fertilization (IVF) often need to do multiple cycles to obtain an euploid embryo and may want to bank embryos for future use. This can become prohibitively expensive. In addition, multiple biopsy sessions add significant time and resource allocation in the embryology laboratory. Combining multiple stimulation cycles vitrified at the 2 pronuclei (2PN) stage together to thaw, culture to blastocyst and biopsy as one group may offer a more cost-effective approach. Investigation is required to confirm thawing of multiple groups of embryos each created from a distinct cycle and vitrified at 2PN provide similar blastocyst rates compared to growing each fresh embryo cohort to blastocyst before biopsy and vitrification.