Salvianolic acid B from Salvia miltiorrhiza bunge: A potential antitumor agent

Sha-Sha Guo,Zhen-Guo Wang

Frontiers in Pharmacology(2022)

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摘要
Salvia miltiorrhiza Bunge (Lamiaceae) is a perennial herb widely found in China since ancient times with a high economic and medicinal value. Salvianolic acid B (Sal-B) is an important natural product derived from Salvia miltiorrhiza and this review summarizes the anticancer activity of Sal-B. Sal-B inhibits tumor growth and metastasis by targeting multiple cell signaling pathways. This review aims to review experimental studies to describe the possible anticancer mechanisms of Sal-B and confirm its potential as a therapeutic drug.
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关键词
TCM,traditional Chinese medicine,salvianolic acid B,anticancer activity,apoptosis,mechanism
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