Dosage compensation: A new player in X chromosome upregulation
Current Biology(2022)
摘要
Dosage balance between sex chromosomes and autosomes can be achieved through diverse mechanisms across vertebrates and invertebrates. A new study discovers a key player that contributes to X chromosome upregulation (XCU) during early mouse development and associates the dysregulation of XCU with human bile duct cancer pathogenesis.
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关键词
upregulation
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