TfOH催化20(S)-喜树碱与腈的酯化反应

Chemical Research and Application(2022)

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Abstract
本文研究了以喜树碱为底物,通过与腈类化合物在酸性条件下反应直接获得20位酯化喜树碱衍生物的方法,该方法避免了常用酯化反应中使用昂贵的催化剂,具有成本低,步骤短,操作方便等优点.
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