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Placebo Response Rates in Randomized Controlled Trials for Perianal Crohn's Disease: A Systematic Review and Meta-Analysis.

Tanmay Sharma,Christopher Ma,Rocio Sedano,Jurij Hanzel,Cassandra McDonald,Malcolm Hogan,Gursimran S Kochhar,Neeraj Narula,Laurent Peyrin-Biroulet,Silvio Danese,John K MacDonald,Vipul Jairath

Journal of Crohn's & colitis（2023）

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Abstract
Placebo response and remission rates in pCD trials are influenced by patient and disease-related factors, as well as the type of intervention being studied. These contemporary rates will inform trial design for novel therapeutics.
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Key words
Peri-anal Crohn’s disease,clinical trials,placebo
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