An FPGA Implementation of A Portable DNA Sequencing Device Based on RISC-V
2022 20th IEEE Interregional NEWCAS Conference (NEWCAS)(2022)
摘要
Miniature and mobile DNA sequencers are steadily growing in popularity as effective tools for genetics research. As basecalling algorithms continue to evolve, basecalling poses a serious challenge for small computing devices despite its increasing accuracy. Although general-purpose computing chips such as CPUs and GPUs can achieve fast results, they are not energy efficient enough for mobile applications. This paper presents an innovative solution, a basecalling hardware architecture based on RISC-V ISA, and after validation with our custom FPGA verification platform, it demonstrates a 1.95x energy efficiency ratio compared to x86. There is also a 38% improvement in energy efficiency ratio compared to ARM. In addition, this study also completes the verification work for subsequent ASIC designs.
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关键词
DNA,Sequencing,RISC-V,ISA,energy-efficiency,Oxford nanopore,basecalling,Viterbi,FPGA,ASIC
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