Cognitive Impairment in Tuberculous Meningitis.

Angharad G Davis,Anna J Dreyer,Christine Albertyn,Mpumi Maxebengula,Cari Stek,Sean Wasserman,Suzaan Marais,Kathleen Bateman,Mark Solms,John Joska,Robert J Wilkinson,Sam Nightingale

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America（2023）

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摘要

Low cognitive performance following HIV-associated TBM is common. This effect is independent of, and additional to, effects of HIV and non-CNS tuberculosis disease. Further studies are needed to understand longer-term outcomes, clarify the association with treatment adherence, a key predictor of outcome in TBM, and develop context-specific tools to identify individuals with cognitive difficulties in order to improve outcomes in TBM.

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关键词

HIV,cognitive impairment,functional impairment,treatment adherence,tuberculous meningitis

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