Predictors of overlapping autoimmune disease in Neuromyelitis Optica Spectrum disorder (NMOSD): A retrospective analysis in two inner-city hospitals.

Milena Rodriguez Alvarez, Aveena Gurung,Vinodkumar Velayndhan,Fernando Cuascut,Samir Alkabie,Latoya Freeman, Ganesh Phayal,Naureen Kabani,Joshy Pathiparampil,Manjeet Bhamra,Alexandra Kreps,Kristaq Koci,Sophia Francis,Su Y. Zhaz Leon,Justin Levinson, Mabelys Rodriguez Lezcano,Abhimanyu Amarnani,Steve Xie,Helen Valsamis,Yaacov Anziska

Journal of the Neurological Sciences（2022）

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摘要

•The coexistence of NMOSD and other autoimmune diseases has worse clinical outcomes and healthcare costs than NMOSD alone.•NMOSD and other autoimmune diseases have higher prevalence and morbidity in Black populations.•We compare clinical data of NMOSD with and without another autoimmune disease in a predominantly Black population.•Grouped-comorbidities, albumin in serum, and platelet count may be independent predictors of AD-NMOSD clinical subtype.

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关键词

Neuromyelitis optica spectrum disorders (NMOSD),Autoimmune disease,Autoantibodies,MRI,AQP4-IgG,Comorbidities,Serum albumin,Logistic regression

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