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Characteristic submucosal alteration in biliary carcinogenesis of pancreaticobiliary maljunction with a focus on inflammasome activation.

Shoko Yamashita,Chie Takasu,Yuji Morine,Hiroki Ishibashi,Tetsuya Ikemoto,Hiroki Mori,Shinichiro Yamada,Takeshi Oya,Koichi Tsuneyama,Mitsuo Shimada

Journal of hepato-biliary-pancreatic sciences（2023）

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Abstract
Activated fibroblasts and M2 macrophages in the GB lamina propria may be associated with biliary carcinogenesis of PBM, possibly through inflammasome activation.
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M2 macrophage,NLRP3,activated fibroblast,biliary cancer,caspase 1
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