Genetic Variants in Histone Modification Regions Predict Clinical Outcomes of Pemetrexed Chemotherapy in Lung Adenocarcinoma.

Yong Hoon Lee,Sook Kyung Do,Shin Yup Lee,Hyo-Gyoung Kang,Jin Eun Choi,Mi Jeong Hong,Jang Hyuck Lee,Sunwoong Lee,Won Kee Lee,Ji Yun Jeong,Kyung Min Shin,Ji Eun Park,Sun Ha Choi,Hyewon Seo,Seung Soo Yoo,Jaehee Lee,Seung Ick Cha, Chang Ho Kim,Jae Yong Park

Oncology（2023）

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摘要

This study suggests that genetic variants in the histone modification regions may be useful for the prediction of clinical outcomes of PEM chemotherapy in advanced lung adenocarcinoma.

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关键词

Chemotherapy response,Genetic variant,Histone modification region,Lung adenocarcinoma,Survival

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