Ginsenoside F2 enhances glucose metabolism by modulating insulin signal transduction in human hepatocarcinoma cells

Shengqiang Han,Long You,Yeye Hu,Shuai Wei,Tingwu Liu,Jae Youl Cho,Weicheng Hu

Journal of Ginseng Research（2022）

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摘要

Overall, GF2 improved glucose metabolism disorders by reducing cellular oxidative stress in IR-HepG2 cells via MAPK signaling, participating in the PI3K/AKT/GSK-3β signaling pathway, promoting glycogen synthesis, and inhibiting gluconeogenesis.

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关键词

Ginsenoside F2, PI3K, AKT signaling pathway, Glucose metabolism

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