Development of a multivariate prediction model to identify individual case safety reports which require clinical review.

Helen R Gosselt, Elizabeth A Bazelmans,Thomas Lieber,Florence P A M van Hunsel,Linda Härmark

Pharmacoepidemiology and drug safety（2022）

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摘要

We developed a prediction model with moderate performances to identify PSTRs with nine commonly available features. Optimisation of the model using more ICSR information (e.g., free text fields) to increase model precision is required before implementation.

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关键词

adverse drug reaction,pharmacovigilance,prediction model,supervised machine learning

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