The expression of metalloproteinases in the lumbar disc correlates strongly with Pfirrmann MRI grades in lumbar spinal fusion patients.
Brain & spine(2022)
摘要
These findings show that disc degradation in DDD is strongly associated with the expression of some metalloproteinases.
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关键词
ADAMT, a disintegrin and metalloproteinases with thrombospondin motif,ADAMTS,AF, annulus fibrosus,DDD, degenerative disc disease,Disc Degeneration,ECM, extracellular matrix,IVD, intervertebral disc,LBP, low back pain,MMP,MMP, matrix metalloproteinase,MRI, magnetic resonance imaging,NP, nucleus pulposus,Real-time PCR,mRNA
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