Shared Knowledge, Gaps and Challenges of Microdosimetry: Realistic Models of Cells and Endoplasmic Reticulum

In the study of the biophysical mechanisms at the basis of the EM field interaction leading to biomedical applications, one needs also to know the field strength at the microscopic scale to establish a quantitative relation between the field and the observed effect. Here authors will show the results on the TMP of the plasma membrane and the endoplasmic reticulum (ER) due a 2D realistic shaping of the ER itself, both analysed in the frequency domain and for an electric pulsed field of 10 ns.