Effects of dose and dose-averaged linear energy transfer on pelvic insufficiency fractures after carbon-ion radiotherapy for uterine carcinoma

Yasumasa Mori,Noriyuki Okonogi,Shinnosuke Matsumoto,Wataru Furuichi,Mai Fukahori,Yuhei Miyasaka,Kazutoshi Murata,Masaru Wakatsuki,Reiko Imai,Masashi Koto,Shigeru Yamada,Hitoshi Ishikawa,Nobuyuki Kanematsu,Hiroshi Tsuji

Radiotherapy and Oncology（2022）

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摘要

•We assessed the prognostic factors for sacrum insufficiency fractures (SIFs) in carbon-ion RT.•Median RBE-weighted dose to the sacrum was a risk factor for SIF.•Neither LET nor physical dose parameters were significant risk factors for SIF.

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关键词

Heavy ions,Fractures,Radiotherapy,Relative biological effectiveness,Linear energy transfer,Uterine cervical neoplasms

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