One-pot synthesis of fluorinated 2-arylchroman-4-one derivatives from 2-(triisopropylsilyl)ethynylphenols and aromatic aldehydes

Larisa Politanskaya,Jiaying Wang,Nadezhda Troshkova,Igor Chuikov,Irina Bagryanskaya

Journal of Fluorine Chemistry（2022）

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摘要

•Directed synthesis of fluorinated 2-arylchroman-4-one derivatives•p-TSA⋅H2O-promouted hydration – condensation – cyclisation process•Two-dimensional NMR characterization of fluorinated O-heterocycles

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关键词

fluorinated flavanones,TIPS-ethynylphenols,p-toluenesulfonic acid,hydration reaction,cycloaddition,NMR analysis

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