Time evolution of cytokine profiles associated with mortality in COVID-19 hospitalized patients.

Laura Sánchez-de Prada,Óscar Gorgojo-Galindo,Inmaculada Fierro,Ana María Martínez-García, Guillermo Sarmentero-López de Quintana, Rocío Gutiérrez-Bustillo, María Teresa Pelaez-Jareño,Elisa Álvarez-Fuente,Esther Gómez-Sánchez,Eduardo Tamayo,Álvaro Tamayo-Velasco,Marta Martín-Fernández

Frontiers in immunology（2022）

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摘要

Hypercytokinemia is a hallmark of COVID-19 but relevant differences between survivors and non-survivors can be early observed. Combinatorial analysis of serum cytokines and chemokines can contribute to mortality risk assessment and optimize therapeutic strategies. Three clusters of cytokines have been identified as independent markers or risk factors of COVID mortality.

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COVID-19,cytokines,hospitalized patients,mortality,principal component analysis - PCA

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