A phase II evaluation of temsirolimus with carboplatin and paclitaxel followed by temsirolimus consolidation in clear cell ovarian cancer: An NRG oncology trial
Gynecologic Oncology(2022)
Abstract
•We evaluated the activity of Temsirolimus with Carboplatin and Taxol Followed by Temsirolimus in Clear Cell Ovarian Cancer.•Median PFS (OS) was 11 (23) months for US/Korea and 12 (26) months for Japan.•Among patients with a response, median duration of response was 20.4 months.•Most common grade 3–4 adverse events were neutropenia, leukopenia, anemia.
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Key words
Clear cell ovarian cancer,Temsirolimus,Asian
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