A phase II evaluation of temsirolimus with carboplatin and paclitaxel followed by temsirolimus consolidation in clear cell ovarian cancer: An NRG oncology trial

Gynecologic Oncology(2022)

Cited 6|Views20
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Abstract
•We evaluated the activity of Temsirolimus with Carboplatin and Taxol Followed by Temsirolimus in Clear Cell Ovarian Cancer.•Median PFS (OS) was 11 (23) months for US/Korea and 12 (26) months for Japan.•Among patients with a response, median duration of response was 20.4 months.•Most common grade 3–4 adverse events were neutropenia, leukopenia, anemia.
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Key words
Clear cell ovarian cancer,Temsirolimus,Asian
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