A rational approach to the CNS tumors diagnostics.

Lenka Krsková, Barbora Šípalová,Tereza Němečková, Martina Strnadová, Tereza Kalendová,Alena Kalfusová, Alexandra, Malkusová, Monika Šandová,Miroslav Koblížek,Jan Balko,Aleš Vícha,Petr Brož,Pavla Jenčová,Lucie Štolová, Dagmar, Voříšková,Marie Belhajová,Michal Zápotocký,David Sumerauer,Josef Zámečník

Ceskoslovenska patologie（2022）

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摘要

The new WHO classification of CNS tumors is largely based on molecular diagnostic. Without molecular methods some entities can no longer be diagnosed. We are trying to show a rational approach to the CNS tumors diagnostics, which is based on conventional molecular methods such as RT-PCR, Sanger sequencing, MLPA, extended by the next generation sequencing (NGS) and methylation SNP array.

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关键词

CNS tumors,MLPA,Methylation SNP array,RT-PCR,WHO classification,next generation sequencing (NGS)

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