Benchmarking state-of-the-art approaches for norovirus genome assembly in metagenome sample

biorxiv(2022)

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摘要
Motivation A recently published article in BMC Genomics by [Fuentes-Trillo et al (2021)][1] contains a comparison of assembly approaches of several Noroviral samples via different tools and preprocessing strategies. Unfortunately the study used outdated versions of tools as well as tools that were not designed for the viral assembly task. In order to improve the suboptimal assemblies the authors suggested different sophisticated preprocessing strategies that seem to make only minor contributions to the results. We redone the analysis using state-of-the art tools designed for viral assembly. Results Here we demonstrate that tools from the SPAdes toolkit (rnaviralSPAdes and coronaSPAdes) allows one to assemble the samples from the original study into a single contig without any additional preprocessing. ### Competing Interest Statement The authors have declared no competing interest. [1]: #ref-5
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关键词
benchmarking,noroviruses,viral assembly
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