Polyunsaturated fatty acids alter the formation of lipid droplets and eicosanoid production in Leishmania promastigotes.

Yasmin Monara Ferreira de Sousa Andrade, Monara Viera de Castro,Victor de Souza Tavares,Rayane da Silva Oliveira Souza,Lúcia Helena Faccioli,Jonilson Berlink Lima,Carlos Arterio Sorgi,Valéria M Borges,Théo Araújo-Santos

Memorias do Instituto Oswaldo Cruz（2023）

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摘要

Our data suggest LD formation and eicosanoid production are distinctly modulated by PUFAS dependent of Leishmania species. In addition, eicosanoid-enzyme mutations are more similar between Leishmania species with same host tropism.

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关键词

lipid droplet,eicosanoid,polyunsaturated fatty acids,GP63,PGF synthase,Leishmania

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