One Way or Another: An Oligorecurrence After an Oligometastasis of an Estrogen Receptor-Positive Breast Cancer

A 52-year-old woman presented with invasive ductal carcinoma of the left breast, cT3 (5.5 cm) cN1 (single axillary level 1 lymph node) cM0, grade 2, estrogen receptor (ER)-positive (70%) progesterone receptor (PR)-negative (0%) Her2/neu-nonamplified. Bone scan obtained at time of diagnosis revealed two lesions within the sternum (1.8 cm × 1.6 cm) and manubrium (2.9 cm × 4.6 cm; Fig. 1). The patient received upfront chemotherapy (dose-dense adriamycin, cyclophosphamide, and paclitaxel) with interval imaging demonstrating partial response in the breast and nodes, and sclerosis of the lytic lesions suggesting response to treatment.