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Central nervous system involvement in systemic lupus erythematosus: Data from the Spanish Society of Rheumatology Lupus Register (RELESSER)

César Magro-Checa,Sofia Ramiro,Iñigo Rúa-Figueroa,Norman Jimenez,Víctor del Campo-Pérez,Julia Martinez-Barrio,María Galindo-Izquierdo,Jaime Calvo-Alén,Esther Uriarte-Isacelaya,Eva Tomero-Muriel,Mercedes Freire-González,Víctor Martínez-Taboada,Eva Salgado,Paloma Vela,Natalia Mena-Vázquez,Alejandro Olivé,Javier Narváez,Raúl Menor-Almagro,Gregorio Santos-Soler,José A Hernández-Beriaín

Seminars in Arthritis and Rheumatism（2022）

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Abstract
•Major CNS NP-SLE contributes to a 2-times higher mortality in SLE.•The individual major CNS NP-SLE manifestations contribute differently to survival in SLE.•CVD and organic brain syndrome are associated with the highest mortality rates.
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Key words
Systemic lupus erythematosus,NP-SLE,Central nervous system,Survival,Mortality
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