Label-Free Direct Mass Spectrometry Analysis of the Bystander Effects Induced in Chondrocytes by Chondrosarcoma Cells Irradiated with X-rays and Carbon Ions.

Antoine Gilbert, Valentin Payet,Benoît Bernay, Elisabeth Chartier-Garcia,Isabelle Testard,Serge M Candéias,François Chevalier

FRONTIERS IN BIOSCIENCE-LANDMARK（2022）

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摘要

All these accessions corresponded to a window of the proteins modulated in response to the bystander effect. Our chondrosarcoma model clarified the nature of the bystander response of chondrocytes and may suggest several interesting new mechanisms that are specific to particular irradiation doses and qualities.

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关键词

IL12,bystander effect,carbon irradiation,chondrosarcoma,proteomic analysis,stress granules

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