Change in c. acnes phylotype abundance and improvement of clinical parameters using a new dermocosmetic product containing myrtus communis and celastrol enriched plant cell culture extracts in patients with acne vulgaris

Introduction: Cutibacterium acnes (C. acnes), the main bacterial species of the pilosebaceous unit, plays a major role in acne. Recent papers demonstrated that specific C. acnes phylotypes were correlated with the severity of inflammatory acne and reported a specific loss of C. acnes phylotype diversity in this context. Objectives: The aim of the study was to evaluate the efficacy of a new dermocosmetic product containing Myrtus communis and Celastrol enriched plant cell culture extracts on C. acnes phylotype abundance and clinical parameters in subjects with mild to moderate acne vulgaris.