CADASIL affects multiple aspects of cerebral small vessel function on 7T‐MRI

Hilde van den Brink,Anna Kopczak,Tine Arts,Laurien Onkenhout,Jeroen C.W. Siero,Jaco J.M. Zwanenburg, Sandra Hein, Mathias Hübner,Benno Gesierich,Marco Duering,Michael S. Stringer,Jeroen Hendrikse,Joanna M. Wardlaw,Anne Joutel,Martin Dichgans,Geert Jan Biessels

Annals of Neurology（2022）

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摘要

Multiple aspects of cerebral small vessel function on 7T-MRI were abnormal in CADASIL patients, indicative of increased arteriolar stiffness and regional abnormalities in reactivity, locally also in relation to white matter injury. These observations provide novel markers of cSVD for mechanistic and intervention studies. ANN NEUROL 2023;93:29-39.

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关键词

cerebral small vessel function,<scp>7t‐mri</scp>

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