New hematological indices as markers of inflammation and high disease activity in patients with systemic lupus erythematosus.

In this study, in addition to hematological markers such as neutrophil/lymphocyte (NLR), platelet/lymphocyte (PLR), monocyte/lymphocyte (MLR) ratio, systemic inflammatory index (SII), systemic inflammation response index (SIRI), and systemic inflammation aggregate index (AISI) were evaluated in systemic lupus erythematosus (SLE) patients. It was aimed to determine the importance of new hematological markers as an inflammation marker in SLE, evaluate the relationship of these parameters with SLE disease activity (DA), and investigate their sensitivity in showing very high DA. 91 SLE patients and 100 healthy controls were included in the study. The Systemic Lupus Erythematosus Disease Activity Index 2000 (SLEDAI-2K) was used to evaluate the DA. SLE patients were divided into patients with SLEDAI-2K