The presence of thrombus in spontaneous coronary artery dissection: A systematic review of autopsy findings

•We independently reviewed images from published autopsies of fatal SCAD•Only one fatal SCAD case had evidence of true lumen thrombus at autopsy (2.5%)•About half of cases involved eosinophilic inflammation (53%)•The role of antiplatelet agents for SCAD should be re-evaluated in clinical trials•The role, treatment implications of eosinophilic inflammation in SCAD are unknown