Polyphenol-Coordinated Supramolecular Hydrogel as a Promising “One-Stop-Shop” Strategy for Acute Infected Wound Treatment
Applied Materials Today(2022)
摘要
•A facile and universal approach is developed for constructing polyphenol-coordinated supramolecular hydrogel through hydrogen bonding and coordination interactions.•Different polyphenol hydrogels are developed and the difficulty to form the hydrogels are compared.•Basic fibroblast growth factor is integrated into the TPFe hydrogel to promote wound healing.•The TPFe hydrogel shows adhesiveness, hemostatic, antioxidant and antibacterial abilities, which may be well adaptive to the different stages of wound repair process.•This “One-Stop-Shop” strategy is a promising method to treat acute infected wound.
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关键词
Hydrogel,Polyphenol,bFGF,“One-Stop-Shop”,Wound treatment
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