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Genetic variations of tumor necrosis factor-α and prostaglandin-endoperoxide synthase 2 genes among Egyptian patients with type 2 diabetes mellitus and diabetic nephropathy

Amany Salah Khalifa,Ahmed Elshebiny,Emad Mohamed Eed,Mohammed G. Elhelbawy,Sara Kamal Rizk

Gene Reports（2022）

Cited 2|Views3
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Abstract
•TNF-α rs361525 is linked to T2DM risk in Egyptian population.•Under multivariate analysis, rs361525 AA and GA significantly affect DM development.•Neither of these SNPs (TNF-α rs361525 & PTGS2 rs689466) is linked to DN.
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Key words
Diabetes mellitus,Diabetic nephropathy,TNF-α,PTG2,Real-time PCR
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