A 2,7-dichlorofluorescein derivative to monitor microcalcifications

Patrik Tholen,Connor Brown,Claudia Keil,Ali Bayir,Hui-Hui Zeng,Hajo Haase,Richard Thompson,Imre Lengyel,Gündoğ Yücesan

Molecular Systems Design & Engineering（2022）

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摘要

Herein, we report the crystal structure of 2,7-dichlorofluorescein methyl ester (DCF-ME) and its fluorescence response to hydroxyapatite binding. The reported fluorophore is very selective for staining the bone matrix and...

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microcalcifications

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