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[SPARC Overexpression Enhances the Sensitivity of SKM-1 Cells to Ara-C by Regulating CPBP/MLKL].

Si-Min Liang,Xiao-Jia Zhou,Duo Cai,Qiao Zhou,Li Wang

Zhongguo shi yan xue ye xue za zhi（2022）

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Abstract
SPARC overexpression enhanced the sensitivity of SKM-1 cells to Ara-C and promoted cell cycle arrest and apoptosis, the mechanism of which may be related to the regulation of CPBP/MLKL pathway.
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Key words
CPBP ,SKM-1 cells ,SPARC gene ,cytarabine arabinoside ,sensitivity
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