Allergic Sensitization Is Crucial for the Suppressive Role of Streptococcus pneumoniae in the Acute Exacerbation of Asthma.

Yuichi Kama,Yoshiyuki Yamada,Takashi Koike,Mayumi Enseki,Kota Hirai,Hiroyuki Mochizuki,Masahiko Kato

International archives of allergy and immunology（2022）

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摘要

Our results suggested that the suppressive effects of S. pneumoniae colonization were observed only in patients with allergic sensitization, wherein serum total IgE, ECP, and IFN-γ may have an important role on acute exacerbation of asthma.

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关键词

Asthma,Bacterial colonization,Cytokine/chemokine,Eosinophilic cationic protein,Streptococcus pneumoniae

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