ID:16045 Simultaneous Deep Brain Stimulation and Responsive Neurostimulation for Drug Refractory Epilepsy: A Case Report Study

Nearly 25% of all epilepsy is Drug Resistant Epilepsy (DRE) 1-3. Surgical evaluation should be considered early in the course of the disease to minimize morbidity and the risk of sudden unexpected death in epilepsy (SUDEP)4-5. Neuromodulation is a viable option when resection or ablation is not feasible. A growing body of evidence shows improved seizure control and long-term efficacy with both7. With highly complex epileptogenic networks, a multimodality approach may provide an additional benefit to maximize seizure control. We report two cases of DRE who underwent anterior nucleus of the thalamus (ANT) DBS implantation followed by RNS implantation. To our knowledge, this is the first report of simultaneous DBS and RNS neurostimulation for the treatment of epilepsy.