Inhibition of advanced glycation end products and protein oxidation by leaf extracts and phenolics from Chilean bean landraces

Felipe Ávila,Nadia Cruz,Jazmin Alarcon-Espósito,Nélida Nina,Hernán Paillan,Katherine Márquez,Denis Fuentealba,Alberto Burgos-Edwards,Cristina Theoduloz,Carmina Vejar-Vivar,Guillermo Schmeda-Hirschmann

Journal of Functional Foods（2022）

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摘要

•Leaf extracts from six Chilean landraces of Phaseolus vulgaris were investigated.•Some 26 compounds were identified from the most active sample by HPLC-MS/MS.•Pearson’s analysis shows strong correlations between phenolics and AGEs inhibition.•Caffeoyl malic acid and rutin synergistically inhibit AGEs and protein oxidation.

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关键词

Phaseolus vulgaris,Protein glycation,Protein crosslinking,Synergic effects,Rutin,Caffeoyl malic acid

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