Formulation optimization and characterization of Pistacia atlantica Desf. essential oil-loaded nanostructured lipid carriers on the proliferation of human breast cancer cell line SKBR3 (in vitro studies)

Journal of Herbal Medicine(2022)

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摘要
•Pistacia atlantica essential oil was successfully loaded on nanostructured lipid carriers.•MTT assay showed that the optimized formulation was more cytotoxic to SKBR3 breast cancer cells.•Pistacia atlantica essential oil-loaded NLCs has the potential to be used in treatment of breast cancer.
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关键词
PAEO,NLC,PAEO-NLC,DLS,ZP,PDI,TEM,EO,NP,DMEM,FBS,DMSO,PBS,MTT 3-(4,PI,OD,IC50,SD,HLB,DW,OA,SA,GMS,SP,T80
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