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Changes in Serum Testosterone and Adrenal Androgen Levels in Transgender Women With and Without Gonadectomy.

Sarah Collet,Noor C Gieles,Chantal M Wiepjes,Annemieke C Heijboer,Tim Reyns,Tom Fiers,Bruno Lapauw,Martin den Heijer,Guy T'Sjoen

The Journal of clinical endocrinology and metabolism（2023）

Cited 5|Views13
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Abstract
Our findings confirm that after an initial drop, testosterone levels in transgender women remain stable. Adrenal androgens decrease in the first year of CPA and estrogen supplementation and remain unchanged after gonadectomy. Androgens did not change after gonadectomy and cessation of CPA. Correlates with clinical symptoms remain to be elucidated.
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Key words
androgens,gender-affirming hormone therapy,gonadectomy,liquid chromatographytandem mass spectrometry,testosterone,transgender women
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