Assessment of dengue virus inactivation in random donor platelets using amotosalen and ultraviolet A illumination.

Ankit Kumar,Aseem Kumar Tiwari,Satendra Kumar,Ashutosh Biswas,Gurpreet Singh,Kabita Chatterjee,Sourit Chakroborty,Sujatha Sunil

Asian journal of transfusion science（2022）

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摘要

Amotosalen/UVA pathogen inactivation treatment showed efficient inactivation of DENV in platelet components. Therefore, it seems to be a promising method for mitigating the risk of dengue transmission through transfusion of potentially contaminated platelet components in dengue-endemic countries such as India.

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关键词

Amotosalen,dengue virus inactivation,photoinactivation,random donor platelets,transfusion,transfusion transmitted infection

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