Omicron neutralizing antibody response following booster vaccination compared with breakthrough infection

Marcel E Curlin,Timothy A Bates,Gaelen Guzman,Devin Schoen,Savannah K McBride,Samuel D Carpenter,Fikadu G Tafesse

Med（2022）

Cited 8|Views8

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Abstract

•SARS CoV-2 antibody responses rise after boosting and after breakthrough infection•Ab responses correlate negatively with age after vaccination but not after breakthrough•Ab-dependent cell-mediated phagocytosis rises 2-fold after boosting or breakthrough•Delta and Omicron BA.1 and BA.2 are progressively less susceptible to neutralization

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Key words

Omicron,antibody,neutralization,COVID-19,vaccination,breakthrough infection,immunity

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