Acquired fluconazole resistance and genetic clustering in Diutina (Candida) catenulata from clinical samples.

Céline Nourrisson,Maxime Moniot,Rose-Anne Lavergne,Estelle Robert,Virginie Bonnin,Ferry Hagen,Frédéric Grenouillet,Claudia Cafarchia,Geraldine Butler,Sophie Cassaing,Marcela Sabou,Patrice Le Pape,Philippe Poirier,Florent Morio

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases（2022）

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摘要

The high rate of acquired fluconazole resistance among clinical isolates of D. catenulata is of concern. In this study, we highlight a link between the genetic diversity of D. catenulata and its antifungal resistance patterns, suggesting possible clonal transmission of resistant isolates.

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关键词

Acquired antifungal resistance,Candida catenulata,Clonal cluster,Diutina catenulata,ERG11,Fluconazole,Microsatellite typing

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