Identifying a selective oligopeptide clamp in the gas phase
CHEMICAL COMMUNICATIONS(2022)
摘要
Oligopeptide foldamers are promising as minimalist functional analogues to proteins. Herein, we report a versatile and cost-effective experimental scheme in the gas phase that can facilely identify selective oligopeptides and unambiguously resolve the corresponding folding conformations. Based on this methodology, a stereoselective oligopeptide clamp targeting beta(2)-blockers is successfully identified.
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关键词
selective oligopeptide clamp,gas phase
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